A study in the 2008 issue of the internet journal of pulmonary medicine, performed on mice, reports that garcinia kola improved respiratory function after 28 days of use of a garcinia extract. Bitter kola seeds were procured from ekeawka market, awka, anambra state. The chemical composition of garcinia kola seed and hull was determined using standard methods. This study investigates the antimicrobial effects of garcinia kola fractions on clinical isolates of multidrug resistant gram negative bacteria and candida. The extract of the seed is ordinarily known as bitter kola. Kolaviron, a garcinia kola biflavonoid complex, protects against ischemiareperfusion injury. Garcinia kola, ovulation, oestrous cycle, foetal development. Garcinia kola also increased the rate of consumption of water, which is also beneficial for weight loss. Files are available under licenses specified on their description page. Adubredu 1forestry research institute of ghana, council for scientific and industrial research knust p. Evaluation of different fractions of garcinia kola extracts against. Garcinia kola is safe taken with or without other foods.
Blood pressure reducing effect of bitter kola garcinia. Pdf nutritional and phytochemical screening of garcinia kola. More studies are in progress and as soon as these studies are published, we will know much more about garcinia kola. The fruit of garcinia kolais collected after falling to the ground and is kept until its orangecoloured velvety skin softens this may take days extracting the nuts is a simple household affair that is. Bitter kola is a highly valued ingredient in african traditional. The extracts of the seed, commonly known as bitter kola figure. Garcinia kola is an edible seed, which belongs to a unique group of plants that. Original research article university of nigeria, nsukka. Cola seeds are sometimes substituted by garcinia kola heckel guttifereae seeds fig. Groups a rats had normal rat chow and water adlibitum while groups b and c rats had garcinia kola. Garcinia has garnered a lot of attention of late as a popular natural weight loss aid.
Adult male wistar rats were treated orally with 100, 200 and 400 mg kg. Antidiabetic effect of methanolic extract of garcinia kola leaves on streptozotocininduced diabetic rats faith ajiebabhio ogbole 1, olamide olajusi. Garcinia kola, generally known in nigeria as bitter kola. In this study the effect of garcinia kola gk on blood pressure was investigated. Diabetes mellitus is the seventh leading cause of death in the united states and it is now a worldwide. Evaluation of the mechanism of action of garcinia kola bitter kola as an ant diabetic. After the first day of administration of the aqueous extract of garcinia kola.
The quest for naturally occurring compounds of herbal or plant origin that. Pertinent mechanistic insights from biochemical and physical evaluations in rat brain. Groups 2 and 3 animals received aqueous extract of garcinia kola every 24 hours for five consecutive days. A study in the 2008 issue of the internet journal of pulmonary medicine, performed on mice, reports that garcinia kola improved respiratory function after 28 days of use of a garcinia. People in western and central africa has been using this plant in their daily aspects of life. Cardioprotective effect of kolaviron garcinia kola seed.
Purine alkaloids and phenolic compounds in three cola. Assessment of the antimicrobial and antioxidant activities. Taking it an hour before or after meals may help to increase the absorption of the key ingredients. Flavonoids of garcinia kola seeds journal of natural. Effects of garcinia kola and azadirachta indica seeds in. It is found in nigeria and its natural habitat is subtropical or tropical moist lowland forests. It is therefore an imperative to study natural compounds with a potential hypoglycemic and antiinflammatory properties, such as garcinia kola seeds. The nutritional analyses involves proximate analyses find. The bitter taste gained the seed its common name bitter kola. Caffeine content of three nigerian cola scholarlink research. Chemical composition of bitter cola garcinia kola seed. Assessment of garcinia kola seed as a natural material for. Garcinia kola seed ameliorates renal, hepatic, and. In this study, milled dried garcinia kola seeds were extracted by the soxhlet extraction method and the antimicrobial activity of the soxhlet extracted diethyl ether.
The suspension was then mixed thoroughly using a clean magnetic stirrer for 5 min to extract the active component, followed by filtration of the solution through a filter paper to remove. The elicitation of no observable histopathological effects by garcinia kola on the histology of the liver is a reflection of its hepatic safety in healthy condition. Bitter kola or garcinia kola is a plant that originated in africa with a plethora of uses. The garcinia genus is a well known tropical plant in the indomalesiana region and mainly distributed in tropical countries including indonesia, thailand, and malaysia.
The main purpose of this study, therefore, is to examine the various uses and outcomes of garcinia kola. Kolaviron is a biflavonoid complex extracted from the seeds of garcinia kola heckel which is commonly known as bitter kola. Garcinia is a source for a revolutionary natural diet ingredient which is currently a rage in america, japan, europe, and other western countries. Garcinia kola extract potentiates a proinflammatory. Drought tolerance of garcinia kola and garcinia afzelii at the seedlings stage t. The powdered form of garcinia kola was sieved to remove the large particles. Despite its socioeconomic importance, cultivation of garcinia kola heckel is very limited due to poor seed germination. Triterpenoids from the bark of garcinia porecta and their. A descriptive crosssectional study on various uses and.
To investigate the antibacterial activity of zingiber officinale ginger garcinia kola bitter kola. Garcinia kola seed is also used in the treatment of liver disease and diarrhea 18,19. O pen access research paper acute administration of. Efficacy of bitter kola for treatment of respiratory.
Diabetes mellitus is the seventh leading cause of death in the united states and it is now a worldwide epidemic. The aim of the present study was to investigate the effects of a crude extract of garcinia kola on male sexual function after subchronic and chronic treatment periods at different sublethal doses. The effect of chronic ingestion of crude garcinia kola on. Drought tolerance of garcinia kola and garcinia afzelii at. Garcinia kola has been used for centuries to treat chest colds in traditional medicine, but research has taken a look and found out why it is effective. Group 3 received aqueous extract of garcinia kola 900 mgkg b. Garcinia kola guttiferae is a largely cultivated tree that is highly valued in west and central africa for its edible nuts. Garcinia kola bitter kola, a name sometimes also used for g. Results show that crude protein, lipid extract, ash, and.
Garcinia kola seeds were procured from a local vendor in bodija market, ibadan, nigeria in april 20. This study was carried out in three districts avrankou, adjarra, and ifangni of southeastern benin, and aimed to analyze the socioeconomic and ethnobotanical importance of garcinia kola. Germination of garcinia kola heckel seeds in response to. Type 1 diabetes t1d is a nonpreventable autoimmune disease where autoreactive t cells orchestrate the destruction of insulinproducing pancreatic beta cells. Most are upperstorey trees, and some are large trees useful for timber. All plants were identified and authenticated by the curator attached to. Journal of current pharma research 4 4, 2014, 12741280.
The nutritional and phytochemical screening of garcinia kola were investigated. However, it toxic dose requires investigation and thus the needs for further studies. Efficacy of bitter kola for treatment of respiratory diseases used as folklore remedies for the treatment of ailments such as liver disorders, hepatitis, diarrhoea, laryngitis, bronchitis and gonorrhoea, ben ukwuoma writes on the promising use of bitter kola in the management of respiratory problems. A case study of garcinia kola nut productiontoconsumption system. Bitter kola has likewise been perceived as an indigenous restorative plant found in rain woods of focal and many west african countries. Clinical effects of garcinia kola in knee osteoarthritis. Garcinia kola heckel and its relatives, including g. Research article the hepatoprotective properties of. Although research is very preliminary, garcinia kola could be a legitimate solution for weight loss. A typical example is garcinia kola, a tropical plant of the african continent which has been the subject of investigation as a potential source of numerous antimicrobial compounds sibanda et al. Garcinia kola exhibits purgative, antiparasitic, antiinflammatory, antibacterial and antiviral properties 20.
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